Osler nodes and Janeway lesions

What do Osler nodes indicate?

Causes. Osler’s nodes result from the deposition of immune complexes. The resulting inflammatory response leads to swelling, redness, and pain that characterize these lesions. The nodes are commonly indicative of subacute bacterial endocarditis.

What are Janeway lesions and Osler nodes?

Classically, Osler’s nodes are on the tip of the finger or toes and painful. Janeway lesions occur on palm and soles and are non-painful. Osler’s nodes are thought to be caused by localised immunological-mediated response while Janeway lesions are thought to be caused by septic microemboli.