The primary function of the centromere is to provide the foundation for assembly of the kinetochore, which is a protein complex essential to proper chromosomal segregation during mitosis.

What are two important functions of centromeres?

The centromeres are the point of attachment of the kinetochore. The main functions include the attachment of sister chromatids, and it is the site for attachment of spindle fibre. Centromeres help in the proper alignment and segregation of the chromosomes during the process of cell division in eukaryotic cells.

What role does the centromere play in mitosis?

The centromere of the chromosome provides a binding site for the mitotic spindle fiber that will attach to each sister chromatid and pull them to opposite ends of the parent cell, which will ultimately become the cytoplasm of the two daughter cells.