Absolutely! Even though you may not see them often, $2 are legal tender, and you can use them at any place that accepts cash.
Are $2 bills worth keeping?
Most large size two-dollar bills issued from 1862 through 1918, are highly collectible and are worth at least $100 in well-circulated condition. Uncirculated large size notes are worth at least $500 and can go up to $10,000 or more.
Do $2 bills increase in value?
Because of its rarity, collectors pay attention to the 2-dollar bill. The rarity doesn't always translate to increased value, but it definitely does sometimes. ... Condition - A 2-dollar bill in uncirculated condition will be worth more than one with significant wear.