Base substitution
Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication. For example, during replication, a thymine nucleotide might be inserted in place of a guanine nucleotide.
Which mutation occurs in base substitution?
Base Substitutions Mutations
A nonsense mutation refers to a base substitution in which the changed nucleotide transforms the codon into a stop codon. Such a change leads to a premature termination of translation, which can badly affect the formation of proteins.
What are 3 things that a substitution mutation causes?
Three things that is caused by Substitution Mutation are:
- This mutation switches one base for another base. Carcinogens are a cause of these nucleotide swaps. this mutation causes-
- Alterations in the coding of amino acids codon to stop codon which results in an incomplete protein.
- Causes Silent mutations.
