Diuretics can stop working and that doesn't mean anything bad necessarily. Different diuretics work on different parts of the kidney. If one stops working or doesn't work as well, your doctor can change up your medications to see if something else works better.

What happens if diuretics don't lower blood pressure?

If diuretics aren't enough to lower your blood pressure, your doctor might add other blood pressure medications to your treatment plan. Diuretics are also used to prevent, treat or improve symptoms in people who have: Heart failure. Liver failure.

How do you treat a diuretic resistance?

Strategies to overcome diuretic resistance include restriction of sodium intake, changes in dose, changes in timing, and combination diuretic therapy.