QT prolongation during lorazepam therapy has not been documented in the literature. We present a case of lorazepam-induced severe QT prolongation.

Does lorazepam prolong QT interval?

Intramuscular haloperidol and intramuscular lorazepam are standard treatments in the acute management of agitation and aggression. Although prolongation of the QT interval and sequelae, including torsade de pointes and death, have been reported for haloperidol (but not lorazepam), formal studies have been lacking.

Do benzodiazepines prolong QT?

The second-generation antipsychotic drugs (i.e., olanzapine, quetiapine, risperidone, and zotepine), mood stabilizers, benzodiazepines, and antiparkinsonian drugs did not prolong the QTc interval.