Although the anti-migraine action of triptans is most effective soon after onset of the headache, treatment during the aura phase has been found to be ineffective.

Do triptans work on migraine auras?

Triptans are most effective if taken early in a migraine attack while the pain is still mild. Triptans should not be taken during the aura phase of a migraine because: Trials in which triptans were administered in the aura phase showed no significant benefit of triptan use over placebo.

Does sumatriptan stop aura?

In a small, four-way crossover open-label study, treatment with sumatriptan 100 mg during aura prevented the development of the headache in 34 out of 38 attacks (89%), and other studies in selected and complicated patients, suggest that triptans may reduce headache when taken during the aura phase [70,71,72].