It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (such as during exercise) thereby increasing walking distance and duration.

How long does it take trental to work?

Trental 400 can take time to work. Your symptoms may improve within 2-4 weeks, however it can take up to 8 weeks to take effect.

What is the mechanism of action of pentoxifylline?

Mechanism of Action

Pentoxifylline increases red blood cell flexibility by increasing erythrocyte ATP and cyclic nucleotide levels. [6] It reduces the viscosity of blood by decreasing erythrocyte aggregation and stimulating fibrinolysis to reduce plasma fibrinogen concentrations.