Capsule is located immediately exterior to the murein (peptidoglycan) layer of gram-positive bacteria and the outer membrane (Lipopolysaccharide layer) of gram-negative bacteria. In electron microscopy, capsule appears like a mesh or network of fine strands.

What is the function of a capsule?

Capsules can protect a bacterial cell from ingestion and destruction by white blood cells (phagocytosis). While the exact mechanism for escaping phagocytosis is unclear, it may occur because capsules make bacterial surface components more slippery, helping the bacterium to escape engulfment by phagocytic cells.

Is capsule present in all bacteria?

Not all bacterial species produce capsules; however, the capsules of encapsulated pathogens are often important determinants of virulence. Encapsulated species are found among both Gram-positive and Gram-negative bacteria.