Skin redness/irritation at the application site, nausea/vomiting, bloating, breast tenderness, headache, or weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Do HRT patches cause bloating?

The progestogen part of HRT is often the one that can give side effects. It can cause premenstrual type symptoms (low mood, irritability, bloating, acne, fatigue, headaches).

Can estradiol cause bloating?

High estrogen and low progesterone levels can lead to water retention and bloating. Estrogen often acts as a fluid retaining hormone, while progesterone is a natural diuretic. Therefore, when these hormones are thrown off balance, you may notice bloating.