Interglobular dentin is especially evident in coronal dentin, near the dentinoenamel junction (DEJ), and in certain dental anomalies, such as in dentinogenesis imperfecta.

What is Interglobular dentin?

Interglobular dentine (IGD) is an area of poorly mineralized dentine matrix. It has been reported that there is an association between the retraction of odontoblast processes (OP) and the formation of IGD. A variation of the extent of OP has been described depending on the region of the tooth and age.

How is Interglobular dentin formed?

Interglobular dentin formation, as described in textbooks of dental histology,' 2 is the result of normal matrix formation but failure of complete fusion of the calcospherites during the calcification period that follows.