They are neither too big nor too aggressive but can bite when mishandled or aggravated in any way. However, one needs to remember that Leopard Gecko bites are very uncommon and hardly hurt. Unless and until there's a reason for biting, Leopard Geckos never bite. And even if they bite, their bites don't draw out blood.

Will my leopard gecko bite me?

Yes, leopard geckos can bite, and babies are more likely to bite you than adults. Some of the reasons for biting include aggressiveness, mistaking your hand for food and being scared or annoyed.

Do leopard geckos like to be held?

Although leopard geckos tolerate being held much better than other reptiles, they don't particularly like it. ... If you take the time to build up trust with your leopard gecko, it won't be afraid or stressed during the handling experience, but they won't look forward to it either.