Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. Granulation process transforms fine powders into free-flowing, dust-free granules that are easy to compress.

What is granulation and how is it used?

Granulation is a process of producing granules generally. In pharmaceutical manufacturing, granulation process implies the techniques that are, used to combine powdered particles to form relatively bigger ones called granules. This process is used for commercial production of tablets.

What causes granulation?

The purpose of dry granulation is to increase the bulk density of powders and increase the particle size to ensure a better flow of distributed material — an important factor in the production of tablets and capsules using high speed manufacturing equipment.