In addition, several over-the-counter products containing retinoids, such as retinol, are available. Because they're not as strong (and thus less irritating), they are not as effective in reducing wrinkles as tretinoin; but they do improve the appearance of photo-aged skin.

What is the strongest over the counter retinol?

Drunk Elephant A-Passioni Retinol Cream is a high-strength retinol cream with peptides, vitamins, and oils to calm and nourish the skin. The Drunk Elephant A-Passioni Retinol Cream formula contains a strong 1% concentration of retinol, which is one of the highest concentrations you can get over-the-counter.

How long does over the counter retinol take to work?

While prescription-strength retinoids may have an effect in a matter of weeks, it can take up to 6 months for OTC retinols to produce the same results. You may notice a difference in conditions like acne after 12 weeks, but sun damage and signs of aging can take much, much longer to improve.