Pseudoephedrine caused statistically significant, but small, increases in systolic blood pressure (1 mm Hg) and heart rate (3 beats/min). No change was observed in diastolic blood pressure.

Does pseudoephedrine make your heart beat faster?

Many over-the-counter decongestants have pseudoephedrine or phenylephrine. These ingredients can cause heart palpitations or raise your blood pressure.

Why does pseudoephedrine make my heart race?

Decongestants and High Blood Pressure

Adrenaline opens your airways, causes your blood vessels to shrink, and moves more blood to your heart and lungs. This makes your heart beat faster and causes your blood pressure to go up. Because decongestants act like adrenaline, they can also raise your blood pressure and pulse.