Bone ossification, or osteogenesis, is the process of bone formation. This process begins between the sixth and seventh weeks of embryonic development and continues until about age twenty-five; although this varies slightly based on the individual.

What is ossification and when does it begin?

bone formation, also called ossification, process by which new bone is produced. Ossification begins about the third month of fetal life in humans and is completed by late adolescence.

Where does ossification first occur?

The first site of ossification occurs in the primary center of ossification, which is in the middle of diaphysis (shaft). The perichondrium becomes the periosteum. The periosteum contains a layer of undifferentiated cells (osteoprogenitor cells) that later become osteoblasts.