Subintimal space in CTO PCI. Historically the subintmal space, which lies between the intima and adventitia, has been feared by coronary interventionalists with the notion that the coronary wire should be steered within the true lumen along the length of a stenosis or occlusion.

What does subintimal mean?

Medical Definition of subintimal

: situated beneath an intima and especially between the intima and media of an artery subintimal hemorrhages.

What is Subintimal angioplasty?

Subintimal angioplasty is a minimally invasive percutaneous technique for the recanalization of occluded lower limb arteries (London 1993; Nydahl 1997). Subintimal angioplasty was first described in 1990 to overcome long and chronic arterial occlusions (Bolia 1990).