In biology, crenation describes the formation of abnormal notched surfaces on cells as a result of water loss through osmosis. ... The cells start to shrivel and form abnormal spikes and notches on the cell membrane. This process is called crenation.

What causes Crenated cells?

Crenated erythrocytes are most commonly caused by excess EDTA (underfilled collection tube), but may also be caused by (a) slow drying, (b) drying in a humid environment, or (c) an alkaline pH from glass slides. When crenation is an artifact, most cells on the slide will exhibit this characteristic.

What is meant by crenation?

1a : a crenate formation especially : one of the rounded projections on an edge (as of a coin) b : the quality or state of being crenate. 2 : shrinkage of red blood cells resulting in crenate margins.