Fludrocortisone can cause high blood pressure, unexplained weight gain, and other changes in the way your kidneys work. If you have a history of heart failure, high blood pressure, or kidney problems, talk to your provider first before using this medication.

Is weight gain a side effect of fludrocortisone?

If you take too much: If you take too much fludrocortisone, you may develop high blood pressure, swelling, loss of potassium, increased heart size, or noticeable weight gain.

What does fludrocortisone do to your body?

Fludrocortisone, a corticosteroid, is used to help control the amount of sodium and fluids in your body. It is used to treat Addison's disease and syndromes where excessive amounts of sodium are lost in the urine. It works by decreasing the amount of sodium that is lost (excreted) in your urine.