Can familiars use/attune to magic Items? Yes they are creatures and can use magic items. They can also attune to them provided the meet any requirements the item has for attunement.

Can familiars use wands?

So the short end of it is "Yes, familiars can use wands. As long as they can hold it in a hand (or whatever passes for a hand for non-humanoids), point it, speak the command word, and succeed at a DC 20 UMD check."

Can familiars interact with objects?

A familiar can take any action that it is capable of other than the Attack action. This includes the Cast A Spell action, Dash, Disengage, Dodge, Help, Hide, Ready, Search, and Use an Object. Since familiars are monsters, they can also take any non-Attack action included in their statblock.