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Does Succinylcholine Trigger Malignant Hyperthermia?
Does Succinylcholine Trigger Malignant Hyperthermia?
Robert Thorne••6 min read
All inhalation anesthetics
inhalation anesthetics
The volatile anesthetics (halothane, isoflurane, desflurane, and sevoflurane) are liquids at room temperature and require the use of vaporizers for inhalational administration. Nitrous Oxide is already under normal conditions of temperature and pressure.
except nitrous oxide are triggers for MH. The muscle relaxant succinylcholine is also a trigger for MH. No other anesthetic drugs
anesthetic drugs
There are 5 main classes of anesthetic agents: intravenous (IV) anesthetics, inhalational anesthetics, IV sedatives, synthetic opioids, and neuromuscular blocking drugs. Each of the classes has particular strengths and weaknesses in attaining the primary goal of general anesthesia.
appear to be triggers, including propofol and ketamine.
Can succinylcholine cause malignant hyperthermia?
Malignant hyperthermia (MH) is an autosomal dominant disorder that may present with a hypermetabolic crisis when susceptible individuals are exposed to volatile anesthetics or succinylcholine.
What medications can trigger malignant hyperthermia?
According to the Malignant Hyperthermia Association of the United States (MHAUS), the following agents approved for use in the U.S. are known triggers of MH: inhaled general anesthetics, halothane, desflurane, enflurane, ether, isoflurane, sevoflurane, and succinylcholine.
