Most experts say that histamine isn't the major cause of a runny nose when you have a cold. Even so, some of the older antihistamines, such as brompheniramine and chlorpheniramine, can bring relief. Newer antihistamines like fexofenadine (Allegra) and loratidine (Claritin) have not been shown to work for cold symptoms.

Does Claritin help with runny nose and congestion?

Claritin (loratadine) is a common over-the-counter (OTC) drug that can help relieve allergy symptoms such as runny nose, sneezing, and itchy eyes. Claritin can also be found as Claritin-D, a combination of loratadine and pseudoephedrine to help fight nasal congestion.

What is the best antihistamine for a cold?

To help relieve a runny nose, itchy and watery eyes, and sneezing associated with the common cold, antihistamines may be considered. First-generation antihistamines including brompheniramine, chlorpheniramine, and clemastine, are preferred over the second-generation antihistamines in the management of these symptoms.