AVISE® CTD is a blood test that can help doctors diagnose lupus and other autoimmune diseases — like rheumatoid arthritis, Sjögren's syndrome, or scleroderma.

How accurate is the Avise test?

The Avise Lupus test had excellent performance characteristics, as compared to the physician's diagnosis, with sensitivity of 83.3%, specificity of 86.4%, positive predictive value of 87.0%, and negative predictive value of 82.6% (positive likelihood ratio: 6.125 and negative likelihood ratio: 0.19).

How accurate is the Avise CTD test?

High levels of EC4d, B-cell-bound C4d (BC4d) and platelet-bound C4d (PC4d) can differentiate SLE from other CTDs with 56%–72% sensitivity and 80%–98% specificity, and from healthy individuals with 60%–81% sensitivity and 91%–100% specificity.