Among the azole group of antifungal medications, imidazoles (miconazole and ketoconazole) are commonly used for localized surface infections and triazoles (itraconazole—for dermatophytes only—fluconazole, voriconazole, and posaconazole) are used for invasive, life-threatening fungal infections.

Where do we use imidazole?

Imidazole is used to elute tagged proteins bound to nickel ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel coordination, freeing the His-tagged proteins.

What does imidazole treat?

An imidazole antifungal used to treat vulvovaginal candidiasis. A broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections. A topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.