Imine formation is a reversible process that starts with the nucleophilic addition of a primary amine to the carbonyl group of an aldehyde or ketone. Next, a proton transfer forms a neutral amino alcohol called a carbinolamine.
Are imines nucleophilic or electrophilic?
The electrophilic carbon atom of aldehydes and ketones can be the target of nucleophilic attack by amines as well as alcohols. double bond is replaced by a C=N double bond, and is known as an imine. ...
Are imines reactive?
Imines are reactive due to their ability to act as electron 'sinks'. The nitrogen of the C=N bond is readily protonated, yielding a protonated imine.