2022 MLB schedule: All teams will start season March 31 if there's no work stoppage. NEW YORK -- Major League Baseball will open the 2022 season March 31 -- as long as there isn't a work stoppage -- and will try for the fourth time to have every team play its first game on the same day for the first time since 1968.

What day is opening day for baseball 2021?

Major League Baseball will begin the 2021 regular season on Thursday, April 1. The Opening Day slate will get underway just after 1 p.m. ET, with the Toronto Blue Jays taking on the New York Yankees in an American League East battle.

Who is playing on Opening Day 2021?

MLB Opening Day 2021 schedule

Cleveland at Detroit Tigers, 1:10 p.m. Minnesota Twins at Milwaukee Brewers, 2:10 p.m. Arizona Diamondbacks at San Diego Padres, 4:10 p.m. Texas Rangers at Kansas City Royals, 4:10 p.m.