Does Nadh Oxidize Pyruvate?

Does Nadh Oxidize Pyruvate?

Pyruvate is produced by glycolysis in the cytoplasm, but pyruvate oxidation

pyruvate oxidation
Pyruvate decarboxylation or pyruvate oxidation, also known as the link reaction (or Oxidative decarboxylation of Pyruvate), is the conversion of pyruvate into acetyl-CoA by the enzyme complex pyruvate dehydrogenase complex. Pyruvate oxidation is the step that connects glycolysis and the Krebs cycle.
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takes place in the mitochondrial matrix (in eukaryotes). ... A carboxyl group is removed from pyruvate and released as carbon dioxide. The two-carbon molecule from the first step is oxidized, and NAD+ accepts the electrons to form NADH.

What is the role of NADH in pyruvate oxidation?

In Summary: Pyruvate Oxidation

During the conversion of pyruvate into the acetyl group, a molecule of carbon dioxide and two high-energy electrons are removed. ... The electrons are picked up by NAD+, and the NADH carries the electrons to a later pathway for ATP production.

What will oxidize pyruvate?

Conversion of Pyruvate into Acetyl-CoA

In a multistep reaction catalyzed by the enzyme pyruvate dehydrogenase, pyruvate is oxidized by NAD+, decarboxylated, and covalently linked to a molecule of co-enzyme A via a thioester bond.

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