Pyruvate is produced by glycolysis in the cytoplasm, but
What is the role of NADH in pyruvate oxidation?
In Summary: Pyruvate Oxidation
During the conversion of pyruvate into the acetyl group, a molecule of carbon dioxide and two high-energy electrons are removed. ... The electrons are picked up by NAD+, and the NADH carries the electrons to a later pathway for ATP production.
What will oxidize pyruvate?
Conversion of Pyruvate into Acetyl-CoA
In a multistep reaction catalyzed by the enzyme pyruvate dehydrogenase, pyruvate is oxidized by NAD+, decarboxylated, and covalently linked to a molecule of co-enzyme A via a thioester bond.