Oral tablet: Each tablet contains 1 mg of ergotamine and 100 mg of caffeine. The typical dose is 2 tablets by mouth as soon as you feel a headache coming on. Take 1 more tablet every 30 minutes as needed. Do not take more than 6 tablets per headache episode or more than 10 tablets per week.

Is ergotamine and caffeine the same thing?

Caffeine is a stimulant that causes narrowing of blood vessels (vasoconstriction). Ergotamine is an ergot alkaloid (ER-got AL-ka-loid) that works by narrowing blood vessels around the brain.

Why is ergotamine combined with caffeine?

The combination of ergotamine and caffeine is used to prevent and treat migraine headaches. Ergotamine is in a class of medications called ergot alkaloids. It works together with caffeine by preventing blood vessels in the head from expanding and causing headaches.