Clinical studies have demonstrated that Excedrin Extra Strength relieves headaches better than Tylenol^® Extra Strength. Both Excedrin Extra Strength and Tylenol^® Extra Strength include acetaminophen, an analgesic that relieves pain and reduces fever.

Can I take Excedrin when I have a fever?

Do not give Excedrin to a child or teenager with a fever, flu symptoms, or chicken pox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children. Do not take more Excedrin than is recommended.

Does Excedrin PM reduce fever?

This combination product contains 2 medications, acetaminophen and an antihistamine. Acetaminophen helps to reduce fever and/or mild to moderate pain (such as headache, backache, aches/pains due to muscle strain, cold, or flu).