Can penicillin go out of date?

Medical authorities state that expired medicine is safe to take, even those that expired years ago. It's true the effectiveness of a drug may decrease over time, but much of the original potency still remains even a decade after the expiration date.

Is Penicillin still good after 2 years?

Official Answer. Amoxicillin capsules and tablets have an expiry of around 2 years and, provided they are stored as recommended and in the original packaging, there will be a small lee way of safety if used beyond expiry.