No. Even though Malignant stars Annabelle Wallis—who is the star of the Conjuring spin-off film, Annabelle, and the subsequent Annabelle sequels—Malignant is a new original film separate from The Conjuring. Wallis's character in Malignant is named Madison.

Is Malignant connected to insidious?

Malignant is not part of The Conjuring universe despite having the same director, James Wan, and actress Annabelle Wallis. Malignant for now is a standalone film in the horror genre and isn't connected to Insidious either.

Is Malignant movie a sequel?

There are no official plans for a Malignant sequel just yet, but you shouldn't rule out the possibility of a Malignant 2. In an interview with GamesRadar.com, Wan was not against the idea of turning Malignant into a franchise but also said that was not his intention.