Escherichia coli cells do not have a discrete nucleus, but they do have a loosely defined area at the center termed the nucleoid that contains most of the DNA.

Does bacteria have a nucleus?

Bacteria lack a membrane-bound nucleus and other internal structures and are therefore ranked among the unicellular life-forms called prokaryotes.

Does E. coli have one cell?

E. coli bacteria are seen after dividing. They are also easy to duplicate and therefore are one of the best-studied prokaryotic organisms. ...