Burke made his final appearance in the third season, leaving Seattle in the aftermath of his failed wedding. ... While mentioned in passing throughout later seasons, Burke officially returns in the tenth season in order to conclude Cristina Yang's departure from the series.

What episode does Yang see Burke again?

On Grey's Anatomy season 10, episode 22, “We Are Never Getting Back Together,” Preston Burke will make his return to the show during a critical time in Cristina's career.

Do Burke and Yang get back together?

During the first season of Grey's Anatomy, Cristina begins dating Preston Burke (Isaiah Washington). Early on in the season, Burke breaks off the relationship because he does not want it to ruin their reputations. When Cristina has a miscarriage, the two get back together.