Cell-mediated immunity is primarily driven by mature T cells, macrophages, and the release of cytokines in response to an antigen. T cells involved in cell-mediated immunity rely on antigen-presenting cells that contain membrane-bound MHC class I proteins in order to recognize intracellular target antigens.

What happens in cell mediated immunity?

Cell-mediated immune responses involve the destruction of infected cells by cytotoxic T cells, or the destruction of intracellular pathogens by macrophages (more...) The activation of naive T cells in response to antigen, and their subsequent proliferation and differentiation, constitutes a primary immune response.

What happens during antibody mediated immunity?

Antibody-mediated immunity involves the activation of B cells and secretion of antibodies when in contact with a pathogen. When exposed to the chemicals released by activated helper T cells, a sensitized B cell divides, producing daughter cells that differentiate into memory B cells and plasma cells.