It is duplicated during S phase of the cell cycle. Just before mitosis, the two centrosomes move apart until they are on opposite sides of the nucleus. As mitosis proceeds, microtubules grow out from each centrosome with their plus ends growing toward the metaphase plate.
What phase do centrosomes duplicate?
The centrosome is duplicated during the S phase. The two centrosomes will give rise to the mitotic spindle, the apparatus that orchestrates the movement of chromosomes during mitosis.
In which phase do centrosome replication begin?
In a normal somatic cell cycle centrosome duplication is first visible during early S-phase, when a new procentriole assembles next to the proximal end of each parental centriole. As the cell progresses through S and G2 phases, daughter centrioles elongate until they reach the length of their parents.
