Consensus sequences for several transcription factors are present on the SUR1 promoter located in the first 140 bp of the 5′-flanking region. They include Sp1, E-boxes, and AP2 Clark and Docherty (1993) Madsen et al (1997) Ashfield and Ashcroft (1998).

Are consensus sequences only found in promoter regions?

The above consensus sequences, while conserved on average, are not found intact in most promoters. On average, only 3 to 4 of the 6 base pairs in each consensus sequence are found in any given promoter.

Are consensus sequence in eukaryotes?

Two consensus sequences occur at fixed positions in promoters from higher eukaryotes and their viruses: the TATA box around -30 and the initiator at the start site of transcription. Both consensus sequences function as positioning elements that control site-specific initiation.