The most common side effects reported during Actos clinical trials were upper respiratory tract infection, headache, sinus infection, muscle pain and sore throat. Other reported side effects included swelling, weight gain, back pain, dizziness, gas and diarrhea.

Is Actos Safe 2021?

Both Actos and its generic equivalent are labeled with a "black box" safety warning to that effect. The drugs also carry a warning of a possible increased risk of bladder cancer based on the FDA's analysis of five-year results from an ongoing, 10-year study in California.

Why is Actos bad?

As it turns out, Actos can cause dangerous side effects other than bladder cancer in patients, including the following: Chronic kidney disease. Congestive heart failure[ Failure of the liver.