Do Sustentacular Cells Secrete Testosterone?

Do Sustentacular Cells Secrete Testosterone?

The Leydig cells

Leydig cells
Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the seminiferous tubules in the testicle. They produce testosterone in the presence of luteinizing hormone (LH).
› wiki › Leydig_cell
make and secrete testosterone, in response to lutenising hormone from the pituitary. ... FSH stimulates the Sertoli cells to secrete androgen-binding protein into the lumen of the seminiferous tubules
seminiferous tubules
The tubuli seminiferi recti (also known as the tubuli recti, tubulus rectus, or straight seminiferous tubules) are structures in the testicle connecting the convoluted region of the seminiferous tubules to the rete testis, although the tubuli recti have a different appearance distinguishing them from these two ...
› wiki › Tubuli_seminiferi_recti
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What do Sustentacular cells secrete?

It is located in the walls of the seminiferous tubules and supplies nutrients to sperm. They are responsible for the differentiation of spermatids, the maintenance of the blood-testis barrier, and the secretion of inhibin, androgen-binding protein and Mullerian-inhibiting factor.

Do Sustentacular cells produce testosterone?

About 30–50 spermatogenic cells are embedded in recesses of each Sertoli cell and migrate from the base toward the lumen of the seminiferous tubules as they mature. ... These cells produce enzymes that convert testosterone to estrogen and to 5α-dihydrotestosterone (DHT).

Sarah Jenkins
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Sarah Jenkins

Sarah Jenkins is a veteran tech journalist with over 12 years of experience covering artificial intelligence, mobile innovations, and digital ethics. Her insights have appeared in leading technology publications worldwide.