An elevated D-dimer level is not normal. It's usually found after a clot has formed and is in the process of breaking down. If you are having significant formation and breakdown of blood clot in your body, your D-dimer may be elevated. A negative D-dimer test means that a blood clot is highly unlikely.

What causes D-dimer levels to rise?

Elevated levels may be seen in conditions in which fibrin is formed and then broken down, such as recent surgery, trauma, infection, heart attack, and some cancers or conditions in which fibrin is not cleared normally, such as liver disease.

What can influence D-dimer?

Overall, advanced age, male gender, and underlying diseases such as hypertension, coronary heart disease, diabetes, and cerebrovascular disease were influencing factors of D-dimer levels which affects the prognosis for COVID-19 patients.