The mechanism of action of 4-aminoquinolines is characterized by the concentration of the drug in the digestive vacuole of the intraerythrocytic parasite.
Why quinine is 4-aminoquinoline give reason?
4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. The compound has been used as a precursor for the synthesis of its derivatives. A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections.
Which anti malarial drug is 4-aminoquinoline derivative?
The four aminoquinoline antimalarial drugs are schizontocidal and gametocytocidal in nature. The four aminoquinolines include chloroquine, amodiaquine, and piperaquine. Primaquine, which is an eight aminoquinoline, acts against hypnozoites.