Macroglossia happens due to the accumulation of adipose tissue in the submucosa of the tongue. Macroglossia in hypothyroidism is due to increased accumulation of subcutaneous mucopolysaccharides due to a decreased degradation.

Can low thyroid cause a swollen tongue?

Hypothyroidism. This thyroid disorder is characterized by low levels of thyroid hormone. When thyroid hormone levels are low, you may experience the following symptoms in addition to tongue swelling and scalloped edges: hair loss.

What are the causes of macroglossia?

Macroglossia is most often caused by an increase in the amount of tissue on the tongue, rather than by a growth, such as a tumor. This condition can be seen in certain inherited or congenital (existing at birth) disorders, including: Acromegaly (buildup of too much growth hormone in the body)