Pyridine is used as a polar, basic, low-reactive solvent, for example in Knoevenagel condensations. It is especially suitable for the dehalogenation, where it acts as the base of the elimination reaction and bonds the resulting hydrogen halide to form a pyridinium salt.

What are pyridine used for?

Pyridine is used to dissolve other substances. It is also used to make many different products such as medicines, vitamins, food flavorings, paints, dyes, rubber products, adhesives, insecticides, and herbicides. Pyridine can also be formed from the breakdown of many natural materials in the environment.

Why pyridine is used in reaction?

Pyridine is used to remove the side product formed in the acylation reaction i.e. HCl from the reaction mixture. ... Pyridine also acts as a nucleophile for the carbonyl group due to its lone pair of electrons on nitrogen atoms which can be delocalized in its ring.