This medication is used to treat infertility in women who do not make enough of a certain natural hormone called progesterone. Progesterone works by preparing the lining of the womb to receive a fertilized egg. This hormone is needed to maintain pregnancy.

Why is micronized progesterone better?

It is well established that progestogens protect the endometrium against the proliferative effects of estrogens in postmenopausal women receiving hormone replacement therapy (HRT). Therefore, micronized progesterone and progestogens are recommended as part of combined HRT in women with an intact uterus.

What is significance of micronized progesterone?

Micronization of the Natural Progesterone increases the half-life of progesterone with the metabolites including Allopregnanolone showing indirect stimulatory effect on progesterone receptor. Micronization decreases particle size and enhances the dissolution of progesterone [4].