It was described in the 18th century by Emanuel Swedenborg. In 1914, Harvey Cushing demonstrated that the CSF was secreted by the choroid plexus.

Who discovered cerebrospinal fluid?

The discovery of CSF is attributed to Emanuel Swedenborg (1688–1772), who had graduated from the University of Upsala, Sweden, with a degree in mining and engineering (Fig. 1⇓), Working as a mining engineer, Swedenborg often came across an underground stream of water that lead him to search for its source.

What is the origin of cerebrospinal fluid?

CSF formation. Most CSF is formed in the cerebral ventricles. Possible sites of origin include the choroid plexus, the ependyma, and the parenchyma[2]. Anatomically, choroid plexus tissue is floating in the cerebrospinal fluid of the lateral, third, and fourth ventricles.