What is acquired keratoderma? Acquired keratoderma is a palmoplantar keratoderma that is NOT inherited as a primary genetic condition. It may occur as part of a generalised skin condition (some of which may be inherited) or as a result of another illness.

Is acquired Keratoderma curable?

Treatment of acquired and hereditary palmoplantar keratoses

There is as yet no cure for hereditary palmoplantar keratoses. In patients with acquired PPK, the cause should be treated (toxins, infection, other factors.) or eliminated, if possible.

How is acquired Keratoderma treated?

If no such etiology is evident, then conservative treatment options include topical keratolytics (urea, salicylic acid, lactic acid), repeated physical debridement, topical retinoids, topical psoralen plus UVA, and topical corticosteroids.