Like other antidepressants, Effexor is commonly associated with weight gain. More than 50 percent of patients taking antidepressants like Effexor report weight gain while taking their medication. Other side effects associated with Effexor commonly include drowsiness, dizziness, nausea, and vomiting.

Is weight gain common with Effexor?

Weight Gain and Antidepressants: Switching Drugs Can Help

Some antidepressants may be less likely to affect weight. Effexor and Serzone generally do not cause weight gain, while Wellbutrin can cause weight loss.

What is the best antidepressant for weight loss?

Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.