Prochlorperazine was approved for medical use in the United States in 1956. It is available as a generic medication. In 2016, it was the 288th most commonly prescribed medication in the United States, with more than a million prescriptions.
Has Compazine been discontinued?
Compazine (prochlorperazine) is also used to treat anxiety, and to control severe nausea and vomiting. The brand name Compazine is discontinued in the U.S. Generic versions may still be available.
When was prochlorperazine invented?
Prochlorperazine was first developed in the 1950s 11 and was first approved by the FDA in 1956. Although newer antiemetic agents such as 5-HT3 antagonists are more heavily promoted, prochlorperazine is still widely used in nausea and vomiting.