The novel ends with Snowman's present-time journey from Paradice back to the Crakers. When he arrives, the Crakers inform him that they saw a group of people like him in the area. Snowman tracks down the other humans and wonders whether to approach them as friends or foes.

How does Oryx Crake die?

Crake tells Jimmy, “I'm counting on you,” then slits Oryx's throat. Jimmy shoots him. ... He kills Oryx, knowing Jimmy will kill him once he does. This leaves Jimmy in charge of raising a new race of humans.

Who kills Oryx in Oryx and Crake?

Jimmy lets them in, whereupon Crake slits Oryx's throat with a knife. Jimmy then immediately shoots Crake dead. During Snowman's journey to scavenge supplies, he cuts his foot on a sliver of glass and becomes infected. He returns to the Crakers' camp and learns that three other humans are camping nearby.