Synaptic cleft is a space between two neurons, connecting them to one another forming a synapse. It is bound on one side by pre-synaptic neuron and. have post-synaptic neuron on the other side. The presynaptic neuron is always. an axon terminal.

What happens at the synaptic cleft quizlet?

The neurotransmitters are in vesicles in the pre-synaptic cell. When the action potential arrives, they are released into the synaptic cleft, and diffuse across to the post-synaptic membrane. ... The ACh diffuses across the synaptic cleft and binds to the receptors on the post-synaptic membrane.

What is in the synaptic cleft at rest?

Inside the axon terminal of a sending cell are many synaptic vesicles. These are membrane-bound spheres filled with neurotransmitter molecules. There is a small gap between the axon terminal of the presynaptic neuron and the membrane of the postsynaptic cell, and this gap is called the synaptic cleft.