Seemingly not fully in control of Eph, Eph arms the nuke and Zach embraces his father before he reaches behind his back to set off the nuke, resulting in the demise and annihilation of the master, Eph, himself and the bodily remains of Quinlan and Palmer.

Who died in the strain?

Nora Martinez dies in the underground train tracks in New York, after the train gets derailed by the Master whose minions serve as cannon fodder.

Does Ephs wife die in the strain?

Zach convinces his mother The Master is just upstairs, inadvertently causing a fight between Eph (who was fixing himself up from injuries sustained at the hands of The Master moments prior) and Kelly, resulting in Kelly's death after Eph is forced to stab her in the brain with a knife.